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Latest Studies on Glucosamine

by Barbara D. Allan
Author of Conquering Arthritis

Glucosamine and chondroitin both have a good track record for helping folks with arthritis. They work well separately, and even better when taken together. The standard therapeutic dose is 1500mg/day of glucosamine and 1200 of chondroitin/day. It generally takes 1- 2 months to start seeing an effect.
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In my latest review of the medical research, I found one study that showed that 1500mg/day of glucosamine for 12 weeks produced noticeable improvements in symptoms in patients with rheumatoid arthritis.

To my surprise, the most recent studies on glucosamine for osteoarthritis are mixed. Some studies show glucosamine reduces osteoarthritis pain and increases joint functionality. Other studies report no effect. This may be because some commercial brands of glucosamine (and chondroitin) do not actually contain the full amount stated on the label.

I noticed the studies indicating that glucosamine had no effect did not verify that the glucosamine and/or chondroitin products they were using really contained the dosages listed on the label.

To avoid buying brands that do not deliver what they promise, it is wise to only buy these supplements from reputable companies, preferably ones with third party certification of the contents.


Glucosamine and Chondroitin:
Which Brands to Avoid, Which to Buy

The June 2006 issue of Consumer Reports describes tests of 17 different brands of glucosamine and chondroitin. Of these, 13 out of the 17 brands contained at least 90% the amounts of glucosamine and chondroitin listed on the label.

The top brand was: Kirkland Signature Extra Strength Glucosamine HCL and Chondroitin Sulfate (Costco), which contained more than 100% of the labeled amounts and cost only $0.25 per day for a therapeutic dose.

Brands ranked 2-5 were:

  • Spring Value Glucosamine & Chondroitin Double Strength (Wal-Mart)
  • Target Triple Strength Glucosamine and Chondroitin Complex
  • Vitamin World Glucosamine Chondroitin Double Strength
  • Vitasmart Double Strength Glucosamine &Chondroitin (Kmart)

A therapeutic dose of these cost between $0.40 and $0.40 per day.

Other brands tested containe adequate amounts of glucosamine and chondroitin but cost as much as $1.25/day for a therapeutic dose.

Consumer Reports characterized two brands as inadequate. This is because they contained significantly less chondroitin than the label said.

These two brands are:

  • FlexAble Glucosamine & Chondroitin Sugar Free Chewables with Vitamin C which had only 60% of the labeled amount of chondroitin
  • Trader Darwin's Glucosamine Chondroitin (Trader Joe's) which had only 10% of the labeled amount.

Website Special

Buy a copy of the book Conquering Arthritis at regular price and receive a free copy the article, 'Researching Promising Arthritis Therapies Using PubMed.'

This article explains how to use a free internet resource to:

  1. verify (or debunk) the scientific claims made for products that claim to help arthritis
  2. check out the track record for various types of arthritis treatments, using the medical literature.

Website Special

→Research the safety and effectiveness of Brand Name Products

→What do you really know about topical liniments?

3 Comments On Latest Studies on Glucosamine

Dear Vijay Soni, what you need to know about supplements to help arthritis is that many are good at helping either undo damage from arthritis or good at lowering inflammation, and thus pain and ongoing damage. Glucosamine is one that helps undo damage. That being said, not every supplement is good for every person. Different people react very differently to different foods and different supplements. It is impossible for me to tell you how long to take glucosamine, because I have no idea how well your body will or will not respond. That being said, if you tolerate it well across time, you can take it safely for as long as it is helping you, which might be months or even years.

Date : 12th Dec 2019   |  By : Barbara Allan
Should I take glucosamine I suffer knee pain since 5 year How many month we take glucosamine

Date : 14th Nov 2019   |  By : Vijay soni
Years ago I began taking glucosamine. Then I developed a painful nodule on top of my penis. This is called Peyrones disease. It seems some men may be prone to this if they take glucosamine. Fortunately, I found a lab in Texas who has developed a topical ointment to dissolve the nodule. Sure beats surgery. Here is the lab's website:

Date : 19th Jul 2018   |  By : Brian Hatch

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